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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
15.45
Human Site:
S708
Identified Species:
28.33
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
S708
K
T
N
N
A
I
S
S
K
R
E
I
L
R
R
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
S708
K
T
N
N
A
I
S
S
K
R
E
I
L
R
R
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
S708
K
T
N
N
A
I
S
S
K
R
E
I
L
R
R
Dog
Lupus familis
XP_543184
1286
146207
S736
K
A
N
S
A
I
S
S
K
R
E
I
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
R662
N
S
A
I
S
S
K
R
E
I
L
R
R
L
N
Rat
Rattus norvegicus
NP_001099552
648
74414
T137
K
S
Q
N
I
F
L
T
K
D
G
T
V
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
A353
R
A
V
E
R
A
E
A
A
R
M
G
G
H
Y
Chicken
Gallus gallus
XP_420401
1281
145243
N722
K
P
D
L
T
M
Q
N
K
R
Q
I
L
K
R
Frog
Xenopus laevis
Q7ZZC8
944
104521
G433
E
G
Q
L
Y
S
F
G
S
D
Y
Y
G
C
L
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
I186
P
Y
N
Q
K
S
D
I
W
A
L
G
C
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
K580
R
K
K
I
E
A
L
K
A
Q
A
N
Q
R
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
K95
D
M
A
E
A
I
K
K
T
N
G
V
H
F
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
E347
A
S
L
R
R
E
W
E
V
K
A
R
L
E
I
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
100
86.6
N.A.
0
20
N.A.
6.6
40
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
20
46.6
N.A.
20
73.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
16
0
39
16
0
8
16
8
16
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
8
0
8
0
0
0
8
0
0
16
0
0
0
0
0
% D
% Glu:
8
0
0
16
8
8
8
8
8
0
31
0
0
8
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
8
0
0
0
0
0
8
0
0
16
16
16
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% H
% Ile:
0
0
0
16
8
39
0
8
0
8
0
39
0
0
8
% I
% Lys:
47
8
8
0
8
0
16
16
47
8
0
0
0
8
0
% K
% Leu:
0
0
8
16
0
0
16
0
0
0
16
0
47
8
24
% L
% Met:
0
8
0
0
0
8
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
39
31
0
0
0
8
0
8
0
8
0
0
8
% N
% Pro:
8
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
16
8
0
0
8
0
0
8
8
0
8
8
0
% Q
% Arg:
16
0
0
8
16
0
0
8
0
47
0
16
8
39
39
% R
% Ser:
0
24
0
8
8
24
31
31
8
0
0
0
0
0
0
% S
% Thr:
0
24
0
0
8
0
0
8
8
0
0
8
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _